1. A dull red, hard, insensitive lesion that is the first manifestation of syphilis.
2. An ulcer located at the initial point of entry of a pathogen.
[French, from Old French, from Latin cancer, tumor, crab; see kar- in the Appendix of Indo-European roots.]
chancrous (-krəs) adj.
The American Heritage® Dictionary of the English Language, Fifth Edition copyright ©2018 by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
Indo-European & Semitic Roots Appendices
Thousands of entries in the dictionary include etymologies that trace their origins back to reconstructed proto-languages. You can obtain more information about these forms in our online appendices:
The Indo-European appendix covers nearly half of the Indo-European roots that have left their mark on English words. A more complete treatment of Indo-European roots and the English words derived from them is available in our Dictionary of Indo-European Roots.