A chronic disorder caused by overproduction of human growth hormone usually by the pituitary gland, characterized by enlargement of the bones of the extremities and the skull and often by the development of complications such as diabetes, hypertension, and osteoarthritis.
[French acromégalie : Greek akron, top, extremity (from neuter of akros, extreme; see ACRO-) + Greek megas, megal-, big; see meg- in the Appendix of Indo-European roots.]
ac′ro·me·galic (-mĭ-gălĭk) adj. & n.
The American Heritage® Dictionary of the English Language, Fifth Edition copyright ©2017 by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
The American Heritage Dictionary Blog
Check out our blog, updated regularly, for new words and revised definitions, interesting images from the 5th edition, discussions of usage, and more.
American Heritage Dictionary Products
The American Heritage Dictionary, 5th Edition
The American Heritage Dictionary of Idioms
The American Heritage Roget's Thesaurus
Curious George's Dictionary
The American Heritage Children's Dictionary
The American Heritage Dictionary of Indo-European Roots
The American Heritage Student Grammar Dictionary
The American Heritage Desk Dictionary + Thesaurus
The American Heritage Science Dictionary
The American Heritage Dictionary of Business Terms
The American Heritage Student Dictionary
The American Heritage Essential Student Thesaurus