Sis·tine (sĭstēn′, sĭ-stēn) also Six·tine (sĭkstēn′, -stīn′)
1. Of or relating to any of the five popes named Sixtus, especially Sixtus IV (1414-1484; reigned 1471-1484) and Sixtus V (1520-1590; reigned 1585-1590).
2. Of or relating to the Sistine Chapel in the Vatican, constructed by Sixtus IV on the site of an earlier chapel.
[Italian sistino, from New Latin sixtīnus, from Medieval Latin Sixtus, the name of several popes, from Latin Sextus, Roman praenomen, from sextus, sixth; see SEXT1.]
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