n. 1.  A letter, especially a formal one. See Synonyms at  letter. 2.  A literary composition in the form of a letter. 3.   Epistle Bible   a.  One of the letters included as a book in the New Testament. b.  An excerpt from one of these letters, read as part of a religious service. [Middle English epistel, from Old French epistle, from Latin epistola, from Greek epistolē, from epistellein, to send a message to : epi-, epi- + stellein, to send; see  stel- in the Appendix of Indo-European roots.]  | 
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