pe·yo·te (pā-ōtē) also pe·yo·tl (-ōtl)
1. A spineless, dome-shaped cactus (Lophophora williamsii) native to Mexico and the southwest United States, having buttonlike tubercles that contain the hallucinogen mescaline and are traditionally used in rituals by certain Native American peoples. Also called mescal.
2. Peyote buttons.
[American Spanish, from Nahuatl peyotl, caterpillar cocoon, peyote (because the tufts of woolly hair in the center of its tubercles resemble caterpillar cocoons).]
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